We can run several CNS injury and degeneration biomarker assays for you on a CRO basis using our in-house developed assays. These have all been described in peer reviewed publications and are now fully validated. We can perform regular ELISA type assays or more sensitive chemiluminescent Meso Scale Discovery (MSD) based assays.

Currently we offer assays to

1. The heavily phosphorylated axonal forms of the major neurofilament subunit NF-H (pNF-H), an excellent marker of axonal loss.

2. Glial fibrillary Acidic Proteins (GFAP), a protein released from damaged and/or degenerating astrocytes.

3. Ubiquitin C-terminal Hydrolase 1 (UCHL1), a protein released from perikarya of damaged or degenerating neurons.

For details of these assays email