August 2019 News

We add new high quality antibodies to the extreme C-terminal peptide of neurofilament NF-L, a rabbit polyclonal RPCA-NF-L-ct. This antibody was made against the extreme C-terminal peptide of rat NF-L coupled to KLH, so the epitopic region is known. This rabbit antibody binds to all mammalian NF-L molecules tested to date. After we epitope mapped our monoclonal antibodies to FOX3/NeuN we found that all of them, and also antibodies made by other companies including the original NeuN monoclonal antibody A66, bind to the same proline rich peptide at the N-terminus of the molecule (see here). We therefore made a new version of our rabbit FOX3 antibody, RPCA-FOX3, raised against this N-terminal peptide. This antibody works well for cell staining and has the advantage over other polyclonal antibodies that the exact epitopic region is known. The peptide used is 100% conserved in most mammalian and avian species so the antibody will have wide utility. Finally we release a new epitope mapped mouse monoclonal antibody to mCherry, MCA-5A6. For epitope information on this antibody see here.